Abstract
Thermoregulatory abnormalities are a major public health problem during exposure to elevated temperatures, especially for the elderly. The proposed research examines mechanisms that can explain the phenomena that lead to heat stroke and death. The main objective of the proposed research is to determine whether the regulatory indicators of human thermoregulation are based on temperature or heat flow by applying thermal stimuli in different body regions and, at the same time, conducting precise measurements of temperature and heat flow. The impact of this work will be significant because it will help us understand the pathophysiological mechanisms of heat stroke and to correlate the progressive changes in heat storage with immune processes and biochemical factors. The PhD student is eager to conduct scientific research and has achieved a lot for this stage of her career, and has the capacity to thrive in any research environment.