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Ph.D Candidate: 
Rovoli Magda
Department: 
Faculty of Veterinary Science
School: 
School of Health Sciences
Supervisor: 
Associate professor Kontopidis George (gkontopidis@vet.uth.gr)
Supervising Committee: 
(1) Kontopidis George (2) Gortzi Olga (3) Pappas Ioannis
See video

The object of this thesis is the association and bioactivity studies of lipophilic vitamins' binding to proteins and lipid mοlecules.

Low solubility of lipophilic vitamins in aqueous solutions is an important problem for their sufficient availability in these media. Encapsulation systems (use of specific proteins and lipid structures (liposomes)) is a promising approach to preserve encapulated lipophilic vitamins' native properties over time and increase concentration in aqueous media but also enhance absorption and bioavailability. Microencapsulation reduces reactivity of lipophilic vitamins with environment (water, oxygen, light), toxicity, degradation and protect them from chamical changes. Proteins with binding site for lipophilic molecules and liposomes can efficiently entrap and deliver-release the encapulated materials.

Lipophilic vitamins are very sensitive molecules, with significant role in nutrient and pharmaceutical products. As a result the need for them to be effectively protected and delivered is of great importance.

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